Publikationen / Patente


N.Gajovic-Eichelmann, J.Ettlinger, B.Micheel, G. Scharte, J.A.Schenk
"Method for electrochemical detection of binding reactions"
Patentanmeldung: EP 10005425

, T. Hillebrand
"Detection of  specific nucleic acid sequences by means
of flurescence quenching"
Patentanmeldung: EP 11755284

, B.Egbert
"Integration of a thermal switch in a lock of a sterile goods holder"
Patentanmeldung: EP 09075446

"Eu/Tb-Chelate-based fluorescence spectroscopic method for detecting analytes"
Patentanmeldung: EP 06742298

, B.Micheel
"Method for the selection of cells producing specifically binding molecules"
Patentanmeldung: EP 03779963


H.T.Hoang, M.Mertens, P.Wessig, F.Sellrie, J.A.Schenk, M.U.Kumke (2018) Antibody Binding at Liposome-Water Interface: A FRET Investigation toward a Liposome-Based Assay. ACS Omega 3, 18109-18116.

U.Eisold, F.Sellrie, H.Memczak, A.Andersson, J.A.Schenk, M.U.Kumke (2018)

Dye Tool Box for a Fluorescence Enhancment Immunoassay. Bioconjugate Chemistry 29, 203-214.


M.Dippong, P.Carl, C.Lenz, J.A.Schenk, K.Hoffmann, T.Schwaar, R.J.Schneider, M.Kuhne (2017) Hapten-Specific Single-Cell Selection of Hybridoma Clones by Fluorescence-Activated Cell Sorting for the Generation of Monoclonal Antibodies. Analytical Chemistry 89, 4007-4012.

U.Eisold, F.Sellrie, J.A.Schenk, C.Lenz, W.F.M.Stöcklein, M.U.Kumke (2015)
Bright or dark immune complexes of anti-TAMRA antibodies for adapted fluorescence-based bioanalysis. Anal Bioanal Chem. 407, 3313-3323. 

C.Tan, J.A.Schenk, N.Gajovic-Eichelmann, F.Sellrie, F.F.Bier (2015) A new one-step antigen heterologous fluorescence immunoassay for progesterone detection in serum. Talanta 134, 508-513.

M.Kuhne, M.Dippong, S.Flemig, K.Hoffmann, K.Petsch, J.A.Schenk, H.J.Kunte, R.J.Schneider (2014) Comparative characterization of mAb producing hapten-specific hybridoma cells by flow cytometric analysis and ELISA. J. Immunol. Meth. 413, 45-56.

F.  Sellrie, C. Lenz, A.Andersson, L.M.Wilhelmsson, J. A.Schenk (2014) Antibody mediated fluorescence enhancement of nucleoside analogue 1,3-diaza-2-oxophenoxazine (tC°). Talanta 124, 67-70.


S. Inal, J. D. Kölsch, F.Sellrie, J.A.Schenk, E.Wischerhoff, A.Laschewsky, D.Neher (2013) A water soluble fluorescent polymer as a dual colour sensor for temperature and a specific protein. J. Mater. Chem. B 1, 6373-6381.

F. Sellrie, E.Graser, C.Lenz, T.Hillebrand,
J.A .Schenk (2013) Specific DNA detection using antibody mediated fluorescence quenching. Biosensors & Bioelectronics 42, 512-515.


M.Stech, H.Merk, J.A.Schenk, W.F.M.Stöcklein, D.Wüstenhagen, B.Micheel, C.Duschl, F.F.Bier, S.Kubick (2012) Production of functional antibody fragments in a vesicle-based eukaryotic cell-free translation system. Journal of Biotechnology 164, 220-231.

J.Ettlinger, J.A.Schenk, B.Micheel, E.Ehrentreich-Förster, N.Gajovic-Eichelmann (2012) A Direct Competitive Homogeneous Immunoassay for Progesterone – the Redox Quenching Immunoassay. Electroanalysis 24, 1567-75.

J.A.Schenk, J.Fettke, C.Lenz, K.Albers, F.Mallwitz, N.Gajovic-Eichelmann, E.Ehrentreich-Förster, E.Kusch, F.Sellrie (2012) Secretory leukocyte protease inhibitor (SLPI) might contaminate murine monoclonal antibodies after purification on protein G. Journal of Biotechnology 158, 34-35.

J.J.Carvalho, M.A.Walter, Y.Baermann-Stapel, M.G.Weller, U.Panne, J.A.Schenk, R.J.Schneider (2012) Non-invasive Monitoring of Selective Immunoglobulins in Mice by Sampling of Faeces. In Vivo 26, 63-69.

F.Sellrie, M.Beck, N.Hildebrandt, B.Micheel (2010) A homogeneous time-resolved fluoroimmunoassay (TR-FIA) using antibody mediated luminescence quenching. Analytical Methods, 2 : 1298-1301. 

A.Linnemann, P.F.van der Ven, P.Vakeel, B.Albinus, D.Simonis, G.Bendas, J.A.Schenk, B.Micheel, R.A.Kley, D.O.Fürst (2010) The Sarcomeric Z-disc Component Myopodin is a Multiadapter Protein that Interacts with Filamin and α-Actinin. European Journal of Cell Biology, 89 : 681-692. 

K.Daskalow, P.Boisguerin, B.Jandrig, F.K.H.van Landeghem, R.Volkmer, B.Micheel, J.A.Schenk (2010) Generation of an Antibody against the Protein Phosphatase 1 Inhibitor KEPI and Characterization of the Epitope. Anticancer Research, 30 : 1573-1578. 

H.Stuckas, K.Messerschmidt, S.Putzler, O.Baumann, J.A.Schenk, R.Tiedemann, B.Micheel (2009) Detection and characterization of gamete-specific molecules in Mytilus edulis using selective antibody production. Molecular Reproduction and Development, 76 (1): 4-10. 

K.Daskalow, P.Boisguerin, B.Jandrig, R.Volkmer, B.Micheel, J.A.Schenk (2008) Epitope mapping of antibodies against S-tagged fusion proteins and molecular weight markers. Bioscience, Biotechnology and Biochemistry 72 (2): 346-351. 

F.Sellrie, B.Micheel (2008) Selection of antibody-producing E.coli cells by means of toxin conjugates. Biochemical Engineering Journal 38 (3): 309-313. 

J.A.Schenk, F.Sellrie, V.Böttger, A.Menning, W.F.M.Stöcklein, B.Micheel (2007) Generation and application of a fluorescein-specific single chain antibody. Biochimie 89 (11): 1304-1311. 

F.Sellrie, J.A.Schenk, O.Behrsing, O.Drechsel, B.Micheel (2007) Cloning and characterization of a single chain antibody to glucose oxidase from a murine hybridoma. Journal of Biochemistry and Molecular Biology 40 (6): 875-880. 

R.Lawatscheck, E.Aleksaite, J.A.Schenk, B.Micheel, B.Jandrig, G.Holland, K.Sasnauskas, A.Gedvilaite, R.G.Ulrich (2007) Chimeric polyomavirus-derived virus-like particles: The immunogenicity of an inserted peptide applied without adjuvant to mice depends on its insertion site and its flanking linker sequence. Viral Immunology 20 (3): 453-460. 

K.Wenzel, K.Daskalow, F.Herse, S.Seitz, U.Zacharias, J.A.Schenk, H.Schulz, N.Hübner, B.Micheel, P.M.Schlag, K.J.Osterziel, C.Özcelik, S.Scherneck, B.Jandrig (2007) The protein phosphatase 1 inhibitor KEPI is down regulated in breast cancer cell lines and tissues and involved in the regulation of the tumour suppressor EGR1 via the MEK-ERK pathway. Biological Chemistry 388: 489-495. 

F. Sellrie, A. Warsinke, B. Micheel (2006) Homogeneous indirect fluorescence quenching immunoassay for the determination of low molecular weight substances. Anal Bioanal Chem. 386(2):206-10. 

P.F.van der Ven, E.Ehler, P.Vakeel, S.Eulitz, J.A.Schenk, H.Milting, B.Micheel, D.O.Furst (2006) Unusual splicing events result in distinct Xin isoforms that associate differentially with filamin c and Mena/VASP. Exp Cell Res. 312(11):2154-67. 

J.A.Schenk, F.Matyssek, B.Micheel (2004) Interleukin 4 increases the antibody response against Rubisco in mice. In Vivo 18, 649-52. 

A.Sheriff, B.Vogt, M.Baumgart, C.Montag, B.Hollenbach, J.A.Schenk, J.Ulrich, F.Elias, B.Micheel (2003) Intracellular capture of B7 in antigen-presenting cells reduces costimulatory activity. Biochemical and Biophysical Research Communications 301, 873-878. 

J.A.Schenk (2002) Two Hybrid cDNA cloning. in: Genetic Library Construction and Screening: Advanced Techniques and Applications. ed. R.C.Bird & B.F.Smith, Springer-Verlag Berlin, Chapter 8, p.145-165.

F.Sellrie, J.A.Schenk, O.Behrsing, V.Böttger, B.Micheel (2002) A competitive immunoassay to detect a hapten using an enzyme-labelled peptide mimotope as tracer. Journal of Immunological Methods 261, 141-144. 

G.Pecher, T.Schirrmann, L.Kaiser, J.A.Schenk (2001) Efficient Cryopreservation of dendritic cells transfected with cDNA of a tumor antigen for clinical application. Biotechnology and Applied Biochemistry 34, 161-166. 

G.Pecher, G.Spahn, T.Schirrmann, H.Kulbe, M.Ziegner, J.A.Schenk, V.Sandig (2001) Mucin (MUC1) cDNA Gene transfer into human Dendritic Cells by cationic Liposomes and recombinant Adenovirus. Anticancer Research 21, 2591-2596.

A.Bergholz, S.Heymann, J.A.Schenk, J.C.Freytag (2001) Biological Sequences Integrated: A Relational Database Approach. Acta Biotheoretica 49 (3), 145-159.

G.Pecher, U.Harnack, M.Günther, M.Hummel, I.Fichtner, J.A.Schenk (2001) Generation of an immortalized human CD4+ T Cell clone inhibiting tumor growth in mice. Biochemical and Biophysical Research Communications 283, 738-742.

J. Schreiber, R. Stahn, J. A. Schenk, U. Karsten, G. Pecher (2000) Binding of tumor antigen mucin (MUC1) derived peptides to the heat shock protein DnaK. Anticancer Research 20, 3093-98.

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